NICOLA Sturgeon has formally asked Theresa May to grant Holyrood the power to hold a second independence referendum, in line with a recent majority vote of MSPs.

In a letter to the Prime Minister, Ms Sturgeon said she felt frustrated that the voices of Holyrood and the other devolved administrations had been “largely ignored and all attempts at compromise rejected” ahead of the UK government triggering Article 50 on Wednesday.

Referring to Mrs May’s intention to withdraw the UK from the EU single market, the First Minister wrote: “That is not an outcome that the people of Scotland voted for. It is also an outcome that will have significant implications for our economy, society and place in the world.

“In these very changed circumstances, the people of Scotland must have the right to choose our own future - in short, to exercise our right of self determination.

“Indeed I noted the importance you attached to the principle of self determination in your [Article 50] letter to [European Council] President Tusk.”

Ms Sturgeon said earlier this month that she wanted to hold a second referendum between autumn 2018 and spring 2019, to allow Scots to choose between Brexit in the UK and independence and a closer relationship with Europe.

Mrs May has already said she will refuse the request, or even discuss a second referendum, until after the Brexit talks are concluded, saying “now is not the time” for such a distraction.

Citing the 69 to 59 vote by the Scottish Parliament on Tuesday in favour of requesting referendum powers under Section 30 of the 1998 Scotland Act, Ms Sturgeon said she wanted to open “early discussions” between the UK and Scottish governments to agree the transfer.

Ms Sturgeon said she noted the Prime Minister’s statements on the issue, but added there appeared to be “no rational reason for you to stand in the way of the will of the Scottish Parliament and I hope you will not do so.

“However, in anticipation of your refusal to enter into discussions at this stage, it is important for me to be clear about my position.

“It is my firm view that the mandate of the Scottish Parliament must be respected and progressed. The question is not if, but how.

“I hope that will be by constructive discussion between our governments. However, if that is not yet possible, I will set out to the Scottish Parliament the steps I intend to take to ensure that progress is made towards a referendum.”

The First Minister also said the Scottish Government would play a “full and constructive role” in securing a good deal for the whole of the UK in the forthcoming Brexit negotiations.

An SNP-commissioned poll this week found most Scots think Holyrood, not Westminster, should have the right to decide whether to hold a second referendum, according to a new poll.

The Survation survey, conducted after Mrs May ruled out a referendum for at least two years, found most Scots also thought London should not be allowed to block a new vote.

The full text of the etter is as follows:

Dear Theresa

When we met in Glasgow on Monday, I wished you well for the negotiations that lie ahead now that you have formally invoked Article 50 of the Lisbon Treaty. I want to reiterate those good wishes now.

I very much hope that you succeed in realising your ambitions for the terms of the UK's future relationship with the EU. A good deal for the UK is clearly in Scotland's interests whatever constitutional future we choose.

It is for that reason that I intend that the Scottish Government will play a full and constructive role in securing such an outcome.

I expressed my frustration on Monday that the process leading up to the invoking of Article 50 had failed to involve the devolved administrations in any meaningful way - a view that I know is shared by the First Minister of Wales.

Far from securing a UK wide approach ahead of invoking Article 50 - as you committed to do last July - the voices of the devolved administrations were largely ignored and all attempts at compromise rejected, in most cases with no prior consultation.

As we move forward into a new phase, we need to agree a more direct role and influence for the devolved administrations, reflecting the key interests that are at stake for all of us.

However, whatever outcome is secured, it seems inevitable that it will remove the UK, not just from the EU, but also from the single market. As you are aware, that is not an outcome that the people of Scotland voted for. It is also an outcome that will have significant implications for our economy, society and place in the world.

In these very changed circumstances, the people of Scotland must have the right to choose our own future - in short, to exercise our right of self determination.

Indeed I noted the importance you attached to the principle of self determination in your letter to President Tusk.

As you are aware, the Scottish Parliament has now determined by a clear majority that there should be an independence referendum. The purpose of such a referendum is to give people in Scotland the choice of following the UK out of the EU and single market on the terms you negotiate, or becoming an independent country, able to chart our own course and build a genuine partnership of equals with the other nations of the UK. A copy of the motion passed by Parliament on 28 March 2017 is attached.

The decision of the Scottish Parliament has been made in line with the tradition of popular sovereignty in Scotland - that the people of Scotland should be able to determine the form of government most suited to their needs - and with the clear commitment in the manifesto on which my government was re-elected last May.

I am therefore writing to begin early discussions between our governments to agree an Order under section 30 of the Scotland Act 1998 that would enable a referendum to be legislated for by the Scottish Parliament.

I have, of course, noted and carefully considered your public position. However, it seems that we are in agreement on the essential matters.

For example we agree that now is not the time for a referendum.

You confirmed to me on Monday, and repeated in your letter invoking Article 50, that you intend the terms of both the UK's exit from the EU and of a future trade deal to be agreed before March 2019 and in time for ratification by other member states - in other words, between the autumn of next year and the spring of 2019. As you are aware, this is the timescale endorsed by the Scottish Parliament for a referendum.

As I have said previously, if the timetable you have set out changes, we will require to consider the implications for the timing of a referendum. However, it seems reasonable at this stage to work on the basis of your stated timetable.

We are also in agreement that - unlike the EU referendum - the choice must be an informed one. That means that both the terms of Brexit and the implications and opportunities of independence must be clear in advance of the referendum.

It is also worth noting that the clear precedent of the 2012 Edinburgh Agreement should make reaching agreement on this occasion a relatively straightforward process - addressing any concern you may have that discussions would be time consuming for your government when they are also preparing for EU negotiations.

In light of the above, there appears to be no rational reason for you to stand in the way of the will of the Scottish Parliament and I hope you will not do so.

However, in anticipation of your refusal to enter into discussions at this stage, it is important for me to be clear about my position.

It is my firm view that the mandate of the Scottish Parliament must be respected and progressed. The question is not if, but how.

I hope that will be by constructive discussion between our governments. However, if that is not yet possible, I will set out to the Scottish Parliament the steps I intend to take to ensure that progress is made towards a referendum.

Again, I wish you well for all that lies ahead and stand ready to discuss both a section 30 order and the Scottish Government's role in securing the best outcome for all parts of the UK.

I am copying this letter to the Presiding Officer of the Scottish Parliament and to Bruce Crawford, Convener of the Parliament’s Finance and Constitution Committee.

Nicola Sturgeon