Dolly The Sheep's legacy still lives on in the world of science 20 years after she was created, according to experts.
Scientists at The Roslin Institute -- who unveiled the sheep in February 1997 after her birth the previous summer - say she still influences their work today.
She was the first mammal to be cloned from an adult animal cell and sparked an intense public debate over the ethics of cloning.
The project also triggered a global media storm and inspired a new generation of scientists.
Dolly also paved the way for previously unimagined possibilities in biology and medicine, providing a cell system for genetic engineering.
Professor Bruce Whitelaw, interim director of the Roslin Institute, worked there when Dolly was created.
He still uses lessons learned from Dolly in his research.
He said: "Cloning enabled gene targeting strategies to be used.
"We have now moved on from using cloning technology and instead use very efficient genetic engineering methods that can be directly applied to the fertilised egg.
"These are based on DNA editing technology which enable extremely precise changes of the genome of animals.
"We apply this exciting method in farm livestock and poultry, aiming to produce animals that are less susceptible to disease."
To create Dolly, scientists took a fully-formed adult sheep cell and effectively turned the clock back to make it behave like a cell from a newly fertilised embryo.
Dr Tilo Kunath, Chancellor's Fellow at the University of Edinburgh's MRC Centre for Regenerative Medicine, was a PhD student in Toronto at the time.
He added: "Dolly really changed our view of biology, showing us that we could take adult cells and reverse them in time.
"Reprogramming cells in this way is something that I use to search for treatments for degenerative conditions like Parkinson's disease.
"Dolly's influence on scientists around the world will continue to impact on cell and tissue repair research for many years to come."
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