US Vice President Joe Biden has announced he would not seek the Democratic nomination for president in 2016, ending months of suspense and removing a huge political obstacle for front-runner Hillary Clinton.
"While I will not be a candidate, I will not be silent," Mr Biden told reporters in the White House Rose Garden with President Barack Obama and the vice-president's wife Jill at his side.
In deciding not to run, Mr Biden, 72, appeared to succumb to his own doubts about whether he and his family were ready for a gruelling campaign while still mourning his son Beau, who died of brain cancer in May. His son had urged him to run.
Mrs Clinton's slipping poll numbers had cracked open a door to a late bid by the affable Mr Biden, leading to calls from his supporters to seek the presidency.
But what was widely hailed as a command performance by Mrs Clinton in the first Democratic TV debate earlier this month turned the tide back in her favor and quieted talk that she was vulnerable in her quest for her party's nomination for the November 2016 election.
Mrs Clinton's support among Democrats surged by 10 percentage points after the October debate, a recent Reuters/Ipsos poll showed. She had the backing of about 52 per cent of poll participants, followed by colourful left-winger Bernie Sanders at 27 per cent. Mr Biden's support, at 13 per cent, was down six percentage points.
Mr Biden had run for president twice before and was a US senator from Delaware for more than three decades.
He is popular with white, working-class voters and he could still play a major role in the election if he chooses to endorse a Democratic candidate.
Also in the running for the Democratic nomination are former Maryland Governor Martin O'Malley and former Rhode Island Governor Lincoln Chafee.
Mr Biden ran for president in 1988 and 2008, both times dropping out early in the race.
He has been prominent for a vice president, with broad involvement in many of President Obama's foreign affairs decisions, such as the withdrawal from Iraq and his Afghanistan strategy.
Mr Biden once boasted that he had "met virtually every major leader in the world."
He became something of a secret weapon for the White House on Capitol Hill, stepping in to negotiate tricky fiscal deals with Republican lawmakers.
Mr Biden, who is Catholic, won praise from human rights groups for saying in May 2012 that he was "absolutely comfortable" with same-sex marriage.
Many observers credited his comments for pushing Mr Obama to announce his support too.
In Mr Biden's long Senate career, he served as chairman of the Foreign Relations Committee. He also pushed for the Violence Against Women Act, which toughened penalties for sex offenders and created protections for victims.
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